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Differing effects of denosumab and alendronate on cortical and trabecular bone

✍ Scribed by Zebaze, Roger M.; Libanati, Cesar; Austin, Matthew; Ghasem-Zadeh, Ali; Hanley, David A.; Zanchetta, Jose R.; Thomas, Thierry; Boutroy, Stephanie; Bogado, Cesar E.; Bilezikian, John P.; Seeman, Ego

Book ID
123148401
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
798 KB
Volume
59
Category
Article
ISSN
8756-3282

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πŸ“œ SIMILAR VOLUMES

Microarchitectural deterioration of cort
Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate
✍ Ego Seeman; Pierre D Delmas; David A Hanley; Deborah Sellmeyer; Angela M Cheung; πŸ“‚ Article πŸ“… 2010 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 424 KB

## Abstract The intensity of bone remodeling is a critical determinant of the decay of cortical and trabecular microstructure after menopause. Denosumab suppresses remodeling more than alendronate, leading to greater gains in areal bone mineral density (aBMD). These greater gains may reflect differ