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Differentiation of the Secondary B-Lymphocyte Repertoire: The Germinal Center Reaction

✍ Scribed by G. J. V. Nossal

Book ID
111247696
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
648 KB
Volume
137
Category
Article
ISSN
0105-2896

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## Abstract Mature B cells, upon activation, progressively differentiate through centroblasts into centrocytes and finally to plasmacytes that express large amounts of selected immunoglobulins. A significant part of this maturation is thought to involve induction of the unfolded protein response (U