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DIFFERENTIATION OF NUCLEUS CELLS ALTERS THEIR RESPONSIVITY TO MECHANICS AND GLUCOSE REDUCTION

โœ Scribed by Antje Mietsch; Cornelia Neidlinger-Wilke; Markus Schultheiss; Marco Brayda-Bruno; Anita Ignatius


Book ID
117135768
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
105 KB
Volume
45
Category
Article
ISSN
0021-9290

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## Abstract Nucleus pulposus intervertebral disc cells are routinely confronted with high osmolality in their microenvironment and respond to this stress in vitro by regulating cell cycle progression and by activating a DNA repair machinery in order to counteract its genotoxic effect. In the presen