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Differentiation of chronic lesions after stroke in stroke-prone spontaneously hypertensive rats using diffusion weighted MRI

✍ Scribed by M. Takahashi; B. Fritz-Zieroth; T. Chikugo; H. Ogawa

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 474 KB
Volume: 30
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910300411

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✦ Synopsis

Abstract

Apparent diffusion coefficients (ADCs) of tissue water were determined in chronic brain lesions of a rat stroke model, stroke‐prone spontaneously hypertensive rats and compared with histology. ADCs increased in the order control < edema < gliosis < cyst. The differences between individual groups were statistically significant. The increase in ADC is thought to mainly reflect a relative increase in the extracellular space in brain tissue. ADC values may be a clinically useful parameter for tissue characterization.

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