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Differentiation of an immortalized CNS neuronal cell line decreases their susceptibility to cytotoxic T cell lysis in vitro

โœ Scribed by Linda A. White; Robert W. Keane; Scott R. Whittemore


Book ID
119108835
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
1005 KB
Volume
49
Category
Article
ISSN
0165-5728

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## Abstract Permanent untransformed cell lines have been established from the cerebral cortex of transgenic mice that carry the polyoma virus large T gene. The immortalized cells described here synthesize laminin and neural cell adhesion molecules and induce primary neurons to develop neuritic proc