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Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver

โœ Scribed by Katja Klugewitz; Stefan Andreas Topp; Uta Dahmen; Toralf Kaiser; Sabine Sommer; Evelyn Kury; Alf Hamann

Book ID
111721748
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
627 KB
Volume
35
Category
Article
ISSN
0270-9139

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Dendritic cells (DC) initiate T cell responses and direct the class of T cell immunity through the production of Th-polarizing cytokines. In the mouse, immunization with CD8alpha(+) DC has led to Th1 priming whereas immunization with CD8alpha(-) DC has been associated with Th2 induction. Here, we us