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Differentiating agents in pediatric malignancies: All-trans-retinoic acid and arsenic in acute promyelocytic leukemia

✍ Scribed by Elizabeth M. Calleja; Raymond P. Warrell

Book ID: 107546012
Publisher: Current Science Inc.
Year: 2000
Tongue: English
Weight: 225 KB
Volume: 2
Category: Article
ISSN: 1523-3790
DOI: 10.1007/s11912-000-0105-x

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## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day all‐__trans__‐retinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AML‐BFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A