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Differentially expressed genes in normal human mammary tissue during tamoxifen therapy (LUD 5646)

✍ Scribed by I. Silva; L. Gebrim


Book ID
117124327
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
334 KB
Volume
70
Category
Article
ISSN
0020-7292

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## Abstract O^6^‐Alkylguanine is a major toxic, mutagenic, and carcinogenic lesion in cellular DNA that is repaired by O^6^‐alkylguanine‐DNA alkyltransferase (ATase). The expression of this gene is directly related to the cellular sensitivity of alkylating agents, with levels of this protein varyin