Differentially expressed genes in giant cell tumor of bone
✍ Scribed by Erica Babeto; André Luis Giacometti Conceição; Marina Curado Valsechi; Paulo Peitl Junior; Débora Aparecida Pires de Campos Zuccari; Luiz Guilherme Cernaglia Aureliano de Lima; Jane Lopes Bonilha; Marília de Freitas Calmon; José Antônio Cordeiro; Paula Rahal
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 474 KB
- Volume
- 458
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Rapid advances in multimodality therapy have not significantly improved the overall 5-yr survival of oral cancer patients in the past two decades, thereby underscoring the need for molecular therapeutics. The development of new treatment strategies for more effective management of oral cancer requir
## Abstract ## BACKGROUND The term __malignant giant cell tumor__ embraces multiple entities and therefore can be confusing. The goals of the current study were to define the clinicopathologic and histologic features of malignancy in giant cell tumors and to clarify the terminology. ## METHODS T
Molecular changes occurring with tumor formation and metastasis need to be identified in order to define novel markers and targets for chemoprevention and therapy. Cell lines from a multistage model of murine squamous cell carcinoma were analyzed for differences in gene expression using mRNA differe
## Abstract Giant cell tumors are heterogeneous tumors consisting of multinucleated giant cells, fibroblast‐like stromal cells and mononuclear histiocytes. The stromal cells have been identified as the neoplastic cell population, which promotes the recruitment of histiocytes and the formation of gi