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Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells

✍ Scribed by Smith, C. M.

Book ID
124080992
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2005
Tongue
English
Weight
385 KB
Volume
315
Category
Article
ISSN
0022-3565

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The flavonoid chrysin is an important dietary substance and induces UGT1A1 protein expression in cell culture. As a representative of the class of dietary flavonoids, clinical investigations have been considered as a means of inducing hepatic UGT1A1 expression. We demonstrate the necessity of a xeno