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Differential transcription of matrix-metalloproteinase genes in primary mouse astrocytes and microglia infected with Theiler’s murine encephalomyelitis virus

✍ Scribed by Jirawat Kumnok; Reiner Ulrich; Konstantin Wewetzer; Karl Rohn; Florian Hansmann; Wolfgang Baumgärtner; Susanne Alldinger

Book ID
111739495
Publisher
Springer US
Year
2008
Tongue
English
Weight
500 KB
Volume
14
Category
Article
ISSN
1355-0284

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Theiler's murine encephalomyelitis virus (TMEV) infection in the central nervous system (CNS) induces a demyelinating disease similar to human multiple sclerosis. TMEV infection results in activation of various chemokine and cytokine genes that are important in the initiation of an inflammatory resp