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Differential sensitivity of metaphase to diamide and ouabain in HeLa cells

โœ Scribed by Michael L. Ziegler; Jesse E. Sisken


Book ID
115891975
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
285 KB
Volume
158
Category
Article
ISSN
0014-4827

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Phenazine methosulfate (PMS) stimulates ouabain-sensitive Rb+ uptake by HeLa cells. This stimulation cannot be attributed to the effect of the dye on the intracellular Na+ or ATP content. Respiratory inhibitors, such as 5 mM NaCN and 5 pM rotenone, and anaerobic conditions enhance the stimulation of