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Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Δ12,14-PGJ2: Role of glutathione

✍ Scribed by Javier Gayarre; Konstantinos Stamatakis; Marta Renedo; Dolores Pérez-Sala


Book ID
116466065
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
376 KB
Volume
579
Category
Article
ISSN
0014-5793

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Cyclopentenone prostaglandins PGA2 and 1
✍ Paul D. Storer; Jihong Xu; Janet A. Chavis; Paul D. Drew 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 321 KB

The cyclopentenone prostaglandin (cPG) 15-deoxy-Delta(12,14)-PGJ(2) (15d-PGJ(2)) has been identified as a potent antiinflammatory agent that is able to inhibit the activation of macrophages and microglia. Additionally, 15d-PGJ(2) is able to ameliorate the clinical manifestations of experimental auto