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Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development

โœ Scribed by Brett A. Colson; Matthew R. Locher; Tanya Bekyarova; Jitandrakumar R. Patel; Daniel P. Fitzsimons; Thomas C. Irving; Richard L. Moss

Book ID
110116989
Publisher
Cambridge University Press
Year
2010
Tongue
English
Weight
416 KB
Volume
588
Category
Article
ISSN
0022-3751

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The mechanism responsible for the regulation of smooth muscle tone at low levels of myosin light chain (MLC) phosphorylation is still poorly understood. According to one model, so-called latchbridges, which contribute to force maintenance at low levels of MLC phosphorylation, are generated by dephos