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Differential Roles of ERK and p38 MAP Kinase Pathways in Positive and Negative Selection of T Lymphocytes

โœ Scribed by Takehiko Sugawara; Tetsuo Moriguchi; Eisuke Nishida; Yousuke Takahama

Book ID
117722970
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
269 KB
Volume
9
Category
Article
ISSN
1074-7613

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Mitogen-activated protein (MAP) kinases have been implicated as important mediators of the inflammatory response. Here we report that c-Jun NH(2)-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38 MAP kinase activities are reprogrammed during the IL-6 induced macrophage-like