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Differential Responses of Protein Kinase C Substrates (MARCKS, Neuromodulin, and Neurogranin) Phosphorylation to Calmodulin and S100

โœ Scribed by F.S. Sheu; F.L. Huang; K.P. Huang


Book ID
115565390
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
752 KB
Volume
316
Category
Article
ISSN
0003-9861

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In gastric chief cells, agents that activate protein kinase C (PKC) stimulate pepsinogen secretion and phosphorylation of an acidic 72-kDa protein. The isoelectric point and molecular mass of this protein are similar to those for a common PKC substrate; the MARCKS (for Myristoylated Alanine-Rich C K