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Differential Requirement for the Stress-Activated Protein Kinase/c-Jun NH2-Terminal Kinase in RNA Damage-Induced Apoptosis in Primary and in Immortalized Fibroblasts

✍ Scribed by Mihail S Iordanov; John Wong; Dianne L Newton; Susanna M Rybak; Robert K Bright; Richard A Flavell; Roger J Davis; Bruce E Magun


Book ID
118769192
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
328 KB
Volume
4
Category
Article
ISSN
1522-4724

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## Abstract Mitogen‐activated protein kinase (MAPK) pathways play central roles in the transduction of extracellular stimuli into cells and the regulation of expression of numerous genes. Docosahexaenoic acid (DHA) was shown to be involved in the regulation of expression of drug metabolizing enzyme