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Differential regulation of PML–RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1

✍ Scribed by Kristin Pietschmann; Marc Buchwald; Sylvia Müller; Shirley K. Knauer; Manfred Kögl; Thorsten Heinzel; Oliver H. Krämer


Book ID
116308120
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
914 KB
Volume
44
Category
Article
ISSN
1357-2725

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## Abstract The stimulation of cell proliferation by insulin like growth factor IGF‐1 has previously been shown to depend on activation of voltage gated K^+^ channels. The signaling involved in activation of voltage gated K^+^ channel Kv1.3 includes the phosphatidylinositol‐3 (PI3) protein kinase,