Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis
β Scribed by Dagmar Scheel-Toellner; Karim Raza; Lakhvir Assi; Darrell Pilling; Emma J. Ross; Wing Yiu Lee; S. John Curnow; Christopher D. Buckley; Arne N. Akbar; Janet M. Lord; Mike Salmon
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 374 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1360-8185
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Although the etiology of intervertebral disc degeneration is poorly understood, one possible approach to regulate the process of intervertebral disc degeneration may include the inhibition of apoptosis. We investigated the antiβapoptotic effects of bclβ2 in nucleus pulposus cells to enh
Lonidamine (LND), a selective inhibitor of the energy metabolism of tumor cells, induces apoptosis, independently of the p53 gene, in the adriamycin(ADR)-resistant MCF7 breast-cancer cell line (MCF7 ADR). On the contrary, LND fails to activate the apoptotic program in the parental MCF7-sensitive cel
## Abstract We have recently demonstrated that BEX2 is differentially expressed in primary breast tumors and BEX2 expression is required for the Nerve Growth factor inhibition of ceramideβinduced apoptosis in breast cancer. In this study we investigate the functional role of BEX2 in the survival an