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Differential Regulation of Notch Ligands in Dendritic Cells upon Interaction with T Helper Cells

✍ Scribed by D. Sauma; P. Espejo; A. Ramirez; A. Fierro; M. Rosemblatt; M. R. Bono


Book ID
110862050
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
376 KB
Volume
74
Category
Article
ISSN
0300-9475

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## Abstract Invariant natural killer T (iNKT) cells regulate the T helper (Th) 1/2 balance and elicit either enhancement or suppression of the immune responses. However, the exact mechanism by which iNKT cells exert these contrasting functions has remained elusive. We demonstrate herein that two ma