Inhibition of interleukin-1β–induced cyc
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Katherine Farrajota; Saranette Cheng; Johanne Martel-Pelletier; Hassan Afif; Jea
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Article
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2005
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John Wiley and Sons
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English
⚖ 313 KB
👁 1 views
Objective. The cyclooxygenase (COX) metabolite, 15-deoxy-⌬ 12,14 -prostaglandin J 2 (15d-PGJ 2 ), has been reported to inhibit the expression of a number of genes involved in the pathogenesis of arthritis. However, its effects on COX-2 remain controversial. We undertook this study to investigate the