𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Differential regulation of IKKα-mediated activation of IRF3/7 by NIK

✍ Scribed by Rui-Peng Wang; Min Zhang; Ying Li; Fei-Ci Diao; Danying Chen; Zhonghe Zhai; Hong-Bing Shu


Book ID
116756750
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
902 KB
Volume
45
Category
Article
ISSN
0161-5890

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Systematic characterization by mass spec
✍ Kiyonaga Fujii; Shingo Nakamura; Kiyohiro Takahashi; Fuyuhiko Inagaki 📂 Article 📅 2010 🏛 Elsevier 🌐 English ⚖ 1011 KB

Interferon regulatory factor 3 (IRF-3) is a critical transcription factor that regulates innate immune responses against viral infection. Upon infection, IRF-3 is activated through phosphorylation of Ser/Thr residues in its C-terminal domain by the kinases, IKK-i and/or TBK-1. This phosphorylation t