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Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver

โœ Scribed by Michael Murray; Rachel M Sefton; Kevin D Croft; Alison M Butler


Book ID
110005984
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
283 KB
Volume
134
Category
Article
ISSN
0007-1188

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Differential regulation of liver P-450II
โœ Joseph C. Kolars; Scott A. Murray; Ken M. Peters; Paul B. Watkins ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 930 KB

Progressive liver fibrosis in rats develops when they are fed a diet deficient in choline. This diet also results in a pronounced and selective decrease in the liver microsomal content of a phase I drug-metabolizing enzyme belonging to the cytochrome P-450111 gene family. Because P-450111 cytochrome