Aging attenuates dynactinβdynein interac
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Nobuyuki Kimura; Osamu Imamura; Fumiko Ono; Keiji Terao
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Article
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2007
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John Wiley and Sons
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English
β 274 KB
## Abstract Impaired axonal transport may promote pathogenesis in neurodegenerative disorders, such as Alzheimer's disease (AD). We previously showed that tau, amyloid precursor protein (APP), and intracellular amyloid Ξ²βprotein (AΞ²) accumulate in the nerveβending fraction of aged monkey brains, pe