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Differential phosphorylation of calreticulin affects AT1 receptor mRNA stability in VSMC

✍ Scribed by Cornelius F.H. Mueller; Kerstin Wassmann; Anja Berger; Stefan Holz; Sven Wassmann; Georg Nickenig


Book ID
116296688
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
276 KB
Volume
370
Category
Article
ISSN
0006-291X

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## Abstract Angiotensin II exerts its cardiovascular effects mainly through the activation of AT~1~ receptors. These receptors can be regulated at a post‐transcriptional level, that is through the modulation of the mRNA stability. This regulation usually involves proteins which are able to bind the