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Differential Phosphoinositide Binding to Components of the G Protein-Gated K+Channel

โœ Scribed by Alison M. Thomas; Sean G. Brown; Joanne L. Leaney; Andrew Tinker


Publisher
Springer
Year
2006
Tongue
English
Weight
459 KB
Volume
211
Category
Article
ISSN
0022-2631

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Whole-cell functional assays are often used for high-throughput screening (HTS) of molecular targets such as ion channels and G-protein-coupled receptors. A common method for assaying the activity of these membrane proteins is to measure the change in intracellular calcium concentration upon recepto