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Differential Patterns of ERK and STAT3 Phosphorylation after Sciatic Nerve Transection in the Rat

โœ Scribed by John Y. Sheu; Doris J. Kulhanek; Felix P. Eckenstein

Book ID
115607366
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
555 KB
Volume
166
Category
Article
ISSN
0014-4886

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Delayed loss of small dorsal root gangli
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โœ Tandrup, Trine; Woolf, Clifford J.; Coggeshall, Richard E. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB ๐Ÿ‘ 2 views

The present study deals with changes in numbers and sizes of primary afferent neurons (dorsal root ganglion [DRG] cells) after sciatic nerve transection. We find that this lesion in adult rats leads to death of some DRG cells by 8 weeks and 37% by 32 weeks after the lesion. The loss of cells appears