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Differential p53-dependent stress response to high and low doses of ultraviolet radiation: DNA repair or apoptosis

✍ Scribed by Li, Gang; Bush, Jason; Ho, Vincent


Book ID
119562128
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
182 KB
Volume
16
Category
Article
ISSN
0923-1811

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p53-Dependent DNA repair and apoptosis r
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p53 plays an essential part in the maintenance of the cellular genetic stability after a DNA-damaging event such as ultraviolet (UV) radiation. Following UV radiation, the amount of p53 protein is elevated. The increased p53 is believed to induce cell cycle arrest, promote nucleotide excision repair