Differential mutagenic response in selected lines ofDrosophila melanogaster
β Scribed by D. L. Palenzona; D. Guerra; P. Casanova
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 218 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-5752
No coin nor oath required. For personal study only.
β¦ Synopsis
The mutagenic efficiency of ionizing radiations has been tested on different lines of Drosophila melanogaster. It has been shown that differential lethal effects are obtained when irradiated females from different lines are mated to flies carrying heterozygous lethal genes. The results seem not to be attributable to differential expression of the lethality in the various crosses performed with the irradiated flies. This might suggest that gene activity is involved in the expression of the mutagenic effects of radiations.
π SIMILAR VOLUMES
Significant changes of genotypic structure in 20 lines selected for wing length are detected by analysis of the allelic frequencies of several enzyme loci (XDH, LAP-D, EST-6, 1-APH, ADH, Ξ±-GPDH). These changes are not haphazard but a consequence of the effects of selection on the genetic structure o
Cells resistant to methotrexate (MTX) were obtained from two established cell lines of D. melanogaster and a karyological analysis was performed. No conspicuous changes in the frequencies of cell types were observed in MTX-resistant (MTXR) subline 0.57, as compared with the original line, whose cell