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Differential modulation of rNaV1.4 channel inactivated states by lidocaine and its charged analogue QX222

✍ Scribed by Péter Lukács; René Cervenka; Xaver Koenig; Ágnes Mike; Michael Kovar; Karlheinz Hilber; Hannes Todt

Book ID
104493197
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
75 KB
Volume
11
Category
Article
ISSN
1471-2210

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The permanently charged lidocaine analog
The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant NaV1.4 channel
✍ Péter Lukács; René Cervenka; Xaver Koenig; Agnés Mike; Touran Zarrabi; Karlheinz 📂 Article 📅 2010 🏛 BioMed Central 🌐 English ⚖ 95 KB

Lukács et al.: The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant Na V 1.4 channel. BMC Pharmacology 2010 10(Suppl 1):A24.