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Differential modulation of human beta-defensin-3 expression in human oral epithelial cells by HPV oncoproteins E6 and E7: potential implication in oral cancer

✍ Scribed by Ge Jin; Emeka Innocent; Brian Chow; Jing Bian; Jacob Dayan; Thomas McCormick; Aaron Weinberg


Book ID
115023336
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
82 KB
Volume
7
Category
Article
ISSN
1750-9378

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## Abstract Infection of cervical keratinocytes by high‐risk HPV is involved in the etiology of cervical carcinoma. Since viral products are immunogenic, development of cancer may require suppression of immune responses directed against infected epithelial cells. Many markers of host immune effecto