Detection of DNA base-excision repair ac
Detection of DNA base-excision repair activity for oxidative lesions in adult rat brain mitochondria
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Dexi Chen; Jing Lan; Wei Pei; Jun Chen
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Article
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2000
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John Wiley and Sons
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English
โ 200 KB
๐ 1 views
Endogenous oxidative damage to brain mitochondrial DNA and consequential disturbances of gene expression and mitochondrial dysfunction have long been implicated in aging and the pathogenesis of neurodegenerative diseases. It has yet to be determined, however, whether mitochondria in brain cells cont