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Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease

โœ Scribed by R. Pollock; V. Chandran; J. Barrett; L. Eder; F. Pellett; C. Yao; M. Lino; S. Shanmugarajah; V. T. Farewell; D. D. Gladman


Book ID
110893374
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
519 KB
Volume
77
Category
Article
ISSN
0001-2815

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## Background: Recent studies have demonstrated an association of a polymorphic (gct)n triplet repeat in the transmembrane (tm) region of the major histocompatibility complex (mhc) class i chain-related gene a (mica), one of the mhc class i chain-related (mic) family members, with some autoimmune d

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## Abstract ## Objective To detect and characterize the autoreactive CD8+ T cells to major histocompatibility complex class I chainโ€“related gene A (MICA), a stressโ€inducible antigen preferentially expressed on the epithelium and endothelium, in patients with Behรงet's disease (BD). ## Methods A c