Differential lysis of tumor target cells displayed by lymphokine activated killer (LAK) cell clones
β Scribed by Pamela Bean; Ravin Agah; Amilabha Mazumder
- Book ID
- 112212349
- Publisher
- AlphaMed Press
- Year
- 1992
- Tongue
- English
- Weight
- 482 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1066-5099
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π SIMILAR VOLUMES
Lymphokine-activated killer (LAK) cells are generated by the culture of peripheral blood lymphocytes with interleukin-2 (IL-2). A variety of cells, including T-lymphocytes and natural killer (NK) cells, can be activated by IL-2 to exhibit the ability to kill multiple tumor and "modified-self" target
The role of CD18, identified as the beta chain of the C D I I family of adhesion glycoproteins, in the lysis of normal autologous monocytes by interleukin-2-activated killer (LAK) cells was explored. The addition of several preparations of anti-CD18 monoclonal antibodies (MAbs) to the incubation mix