Interactions of phosphatidylinositol 3-k
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Nobuyuki Okishio; Masako Nagai; Ryuji Fukuda; Shigenori Nagatomo; Teizo Kitagawa
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Article
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2000
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Wiley (John Wiley & Sons)
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English
⚖ 221 KB
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Absorption, circular dichroism (CD), and UV resonance Raman (UVRR) spectroscopies were applied to selectively examine the environmental and structural changes of Trp and Tyr residues in the phosphatidylinositol 3-kinase (PI3K) SH3 domain induced by ligand association. Comparison of the spectra of PI