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Differential inhibition of interleukin 2- and interleukin 4-mediated human B cell proliferation by ionomycin: A possible regulatory role for apoptosis

✍ Scribed by Aimé Vazquez; Marie Thérèse Auffredou; Nadia Chaouchi; Joelle Taieb; Surendra Sharma; Pierre Galanaud; Gérald Leca


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
716 KB
Volume
21
Category
Article
ISSN
0014-2980

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We analyzed the effects of interleukin 2 (IL2) and IL4 isolated and in association on the specific response of human B cells triggered by trinitrophenylated polyacrylamide beads (TNP-PAA). IL2 induced an increase (more than 10 times) in the number of hapten-binding cells [detected by a rosette-formi