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Differential Induction of Heme Oxygenase-1 in Macrophages and Hepatocytes during Acetaminophen-Induced Hepatotoxicity in the Rat: Effects of Hemin and Biliverdin

โœ Scribed by Hawjyh Chiu; Jennie A. Brittingham; Debra L. Laskin


Book ID
112268578
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
828 KB
Volume
181
Category
Article
ISSN
0041-008X

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## Abstract Stress response genes including heat shock proteins are induced under a variety of conditions to confer cellular protection. This study investigated the role of calcium signaling in the induction of two stress response genes, heme oxygenase-1/hsp32 and hsp70, in isolated rat hepatocytes