Differential impairment of glucagon responses to hypoglycemia, neuroglycopenia, arginine, and carbachol in alloxan-diabetic mice

Impairment of contractile response to ca

Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice

✍ Marie-Louise Soulié; Gérard Cros; Jean-Jacques Serrano; Jean-Pierre Bali 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 331 KB

This work explored the role of the cholinergic pathway, assessed at a post-synaptic level by the use of isolated smooth muscle cells, in the impairment of antral motility associated with diabetic gastroparesis. Contractile response to carbachol--but not to erythromycin, a motilin receptor agonist--w