Differential gene expression in normal esophagus and Barrett’s esophagus
✍ Scribed by Jacob Wang; Rong Qin; Yan Ma; Huiyun Wu; Heiko Peters; Matthew Tyska; Nicholas J. Shaheen; Xiaoxin Chen
- Publisher
- Springer Japan
- Year
- 2009
- Tongue
- English
- Weight
- 887 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0944-1174
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Esophageal carcinoma includes squamous cell carcinoma and Barrett's adenocarcinoma. The latter usually develops from a premalignant lesion named Barrett's esophagus. MUC genes are known to be specifically expressed in the normal, premalignant and malignant epithelia of various tissues. The aim of th
Barrett's esophagus (BE) is a metaplastic change of the squamous esophageal epithelium to columnar gastric or intestinal-like epithelium. BE is associated with long-standing gastroesophageal reflux disease and carries an increased risk for dysplasia and adenocarcinoma. Little if any is known regardi