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Differential function of major histocompatibility complex antigens in T-lymphocyte activation

✍ Scribed by Bach, Fritz H.; Bach, Marilyn L.; Sondel, Paul M.


Book ID
109698043
Publisher
Nature Publishing Group
Year
1976
Tongue
English
Weight
1007 KB
Volume
259
Category
Article
ISSN
0028-0836

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The activation requirements for antigen-dependent proliferation of CD4+ T cells are well documented,while the events leading to the inactivation phase are poorly understood. Here, we tested the hypothesis that the lymphocyte-activation gene 3 (LAG-3), a second major histocompatibility complex (MHC)