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Differential expression of α-2,3-sialyltransferases and α-1,3/4-fucosyltransferases regulates the levels of sialyl Lewis a and sialyl Lewis x in gastrointestinal carcinoma cells

✍ Scribed by A.S. Carvalho; A. Harduin-Lepers; A. Magalhães; E. Machado; N. Mendes; L.T. Costa; R. Matthiesen; R. Almeida; J. Costa; C.A. Reis

Book ID: 116307820
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 963 KB
Volume: 42
Category: Article
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2009.09.010

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## Abstract Gangliosides are sialic acid–containing glycosphingolipids that are associated with tumor malignancy and progression. Among the enzymes required for the production of gangliosides, sialyltransferases have received much attention in terms of their relationship with cancer. In our previou