Expression ofMet protein and urokinase-t
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Zanetti, Antonio; Stoppacciaro, Antonella; Marzullo, Antonella; Ciabatta, Maria;
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Article
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1998
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John Wiley and Sons
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English
⚖ 314 KB
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Met protein encoded by MET oncogene is the high affinity receptor for hepatocyte growth factor (HGF)/scatter factor (SF). HGF/SF has to be cleaved in its heterodimeric form by the urokinase-type plasminogen activator (uPA) to become active as a ligand for Met receptor. The expression of Met protein