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Differential expression of the components of the plasminogen activating system in human thyroid tumour derived cell lines and papillary carcinomas

✍ Scribed by S. Ulisse; E. Baldini; M. Toller; E. Marchioni; L. Giacomelli; E. De Antoni; E. Ferretti; A. Marzullo; F.M. Graziano; P. Trimboli; L. Biordi; F. Curcio; A. Gulino; F.S. Ambesi-Impiombato; M. D’Armiento


Book ID
116429023
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
289 KB
Volume
42
Category
Article
ISSN
0959-8049

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Met protein encoded by MET oncogene is the high affinity receptor for hepatocyte growth factor (HGF)/scatter factor (SF). HGF/SF has to be cleaved in its heterodimeric form by the urokinase-type plasminogen activator (uPA) to become active as a ligand for Met receptor. The expression of Met protein