Cyclin-D1 over-expression represents one of several common alterations in the G 1 -S transition associated with malignancies. Conclusive evidences indicate that cyclin D1 is a proto-oncogene and the gene is amplified or rearranged in different tumour types. Since very little is known about aberratio
Differential expression of potassium ion channels in human renal cell carcinoma
β Scribed by Surbhi Wadhwa; Pankaj Wadhwa; Amit K. Dinda; Narmada P. Gupta
- Publisher
- Springer Netherlands
- Year
- 2008
- Tongue
- English
- Weight
- 598 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0301-1623
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Accumulating evidences indicate that cyclooxygenase (COX)β2 plays an important role in tumorigenesis in many human cancers. Yet the relationship between COXβ2 and human renal cell carcinoma (RCC) remains unclear. The aim of our study was to evaluate COXβ2 expression in human RCC cell li
In a recent paper, we described the expression pattern of proto-oncogenes in primary human renal cell carcinoma [12]. To test the possibility of using xenografts as a useful alternative for such studies, we analyzed xenografts of a number of human renal cell carcinomas in nu/nu mice. Xenografts incl
## Abstract Ca^2+^βactivated K^+^ (K~Ca~) channels are a unique family of ion channels because they are capable of directly communicating calcium signals to changes in cell membrane potential required for cellular processes including but not limited to cellular proliferation and migration. It is no