✦ LIBER ✦

Differential expression of peroxiredoxin subtypes in human brain cell types

✍ Scribed by Theodore A. Sarafian; M. Anthony Verity; Harry V. Vinters; Charles C.-Y. Shih; Liangru Shi; Xiang Dong Ji; Lingpu Dong; Hungyi Shau

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 90 KB
Volume: 56
Category: Article
ISSN: 0360-4012
DOI: 10.1002/(sici)1097-4547(19990415)56:2<113::aid-jnr1>3.0.co;2-k

No coin nor oath required. For personal study only.

✦ Synopsis

The metals iron (Fe) and manganese (Mn) are essential for normal functioning of the brain. This review focuses on recent developments in the literature pertaining to Fe and Mn transport. These metals are treated together because they appear to share several transport mechanisms. In addition, several neurological diseases such as Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease are all associated with Fe mismanagement in the brain, particularly in the striatum and basal ganglia. Similarly, Mn accumulation in brain also appears to target the same brain regions. Therefore, stringent regulation of the concentration of these metals in the brain is essential. The homeostatic mechanisms for these metals must be understood in order to design neurotoxicity prevention strategies.

📜 SIMILAR VOLUMES

Differential expression of peroxiredoxin

Differential expression of peroxiredoxin subtypes in human brain cell types

✍ Theodore A. Sarafian; M. Anthony Verity; Harry V. Vinters; Charles C.-Y. Shih; L 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB

The peroxiredoxin (Prx) protein is expressed widely in animal tissues and serves an antioxidant function associated with removal of cellular peroxides. We have cloned two Prx genes and observed differential expression of Prx-I and Prx-II (formerly NKEF-A and NKEF-B) in purified rat brain cell cultur

Differential expression of peroxiredoxin

Differential expression of peroxiredoxin subtypes in human brain cell types

✍ Theodore A. Sarafian; M. Anthony Verity; Harry V. Vinters; Charles C.-Y. Shih; L 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

Expression of somatostatin receptor subt

Expression of somatostatin receptor subtypes in human brain tumors

✍ Anne Dutour; Ujendra Kumar; Rosemarie Panetta; L'Hovicine Ouafik; Federic Fina; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 261 KB 👁 1 views

Expression of mRNA for the 5 somatostatin receptors (sst 1-5 ) was characterized by Northern blot and RT-PCR analysis in 20 meningioma and 9 glioma samples. sst 1 mRNA was detectable by Northern blots of poly-A ؉ RNA in meningiomas but not gliomas. In contrast, sst 2 mRNA was readily detected by Nor

Expression and significance of urokinase

Expression and significance of urokinase type plasminogen activator gene in human brain gliomas

✍ Xiang Zhang; Zhou Fei; Xing-yao Bu; Hai-ning Zhen; Zhi-wen Zhang; Jian-wen Gu; Y 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB

## Background and objectives: Urokinase type plasminogen activator (upa) regulates a variety of processes involved in tissue morphogenesis, cell differentiation, migration and invasion. we analyzed the available informations to better interpret the pathogenetic relationship between upa activity and

Differential expression and distribution

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells

✍ Carlo Ramoni; Francesca Luciani; Francesca Spadaro; Luana Lugini; Francesco Lozu 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 297 KB

Differential expression of human ferriti

Differential expression of human ferritin H chain gene in immortal human breast epithelial MCF-10F cells

✍ Nadia A. Higgy; Ana M. Salicioni; Irma H. Russo; Pei Li Zhang; Jose Russo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB 👁 1 views

Subtractive hybridization was used to isolate genes expressed uniquely in the immortalized human breast epithelial cell (HBEC) line MCF-10F and not in the mortal HBEC line S-130, from which MCF-10F cells were derived. We identified a 233-bp cDNA that was expressed in MCF-10F cells and not in their m