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Differential expression of myc family genes during murine development

✍ Scribed by Zimmerman, Kathryn A.; Yancopoulos, George D.; Collum, Robert G.; Smith, Russell K.; Kohl, Nancy E.; Denis, Kathleen A.; Nau, Marion M.; Witte, Owen N.; Toran-Allerand, Dominique; Gee, Connie E.

Book ID
109742814
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
588 KB
Volume
319
Category
Article
ISSN
0028-0836

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## Abstract Mad proteins (Mad1, Mxi1, Mad3, Mad4, Mnt/Rox) are biochemical and biological antagonists of c‐Myc oncoprotein. Mad‐Max dimers repress the transcription of the same target genes activated by Myc‐Max dimers. Despite the critical role of Max and Mad proteins as modulators of c‐Myc functio