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Differential expression of mismatch repair proteins, MLH1 and MSH2, in Transitional Cell Carcinoma (TCC) of the bladder

✍ Scribed by James Catto; George Xinarianos; Julian Burton; Mark Meuth; Freddie Hamdy

Book ID
118643454
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
167 KB
Volume
1
Category
Article
ISSN
1569-9056

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## Background: Several convincing studies have shown that the hmsh2 gene plays major roles in mismatch repair by recognizing mismatched bases and preventing mutations during dna replication. loss of this function may result in the accumulation of dna replication errors or even the mutator phenotype

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