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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

✍ Scribed by Spink, D.

Book ID
121821525
Publisher
Oxford University Press
Year
1998
Tongue
English
Weight
442 KB
Volume
19
Category
Article
ISSN
0143-3334

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Elevated expression of cytochrome P450 1B1 (CYP1B1) and estradiol 4-hydroxylation have been reported to be biomarkers of tumorigenesis in humans. The aromatic hydrocarbon receptor (AhR) regulates expression of human cytochrome P450 1A1 (CYP1A1) and CYP1B1, 17␀-estradiol (E 2 ) 2-and 4-hydroxylases,