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Differential expression of cGMP-inhibited cyclic nucleotide phosphodiesterases in human hepatoma cell lines

✍ Scribed by Taku Murata; Masato Taira; Vincent C. Manganiello

Book ID
115932367
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
568 KB
Volume
390
Category
Article
ISSN
0014-5793

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## Abstract During the perinatal period, lungs undergo changes to adapt to air breathing. The genes involved in these changes are developmentally regulated by various signaling pathways, including the cyclic nucleotide cAMP. As PDE4s are critical enzymes for regulation of cAMP levels, the objective