Differential expression of cell surface integrins on human mast cells and human basophils
β Scribed by W. R. Sperr; H. Agis; K. Czerwenka; W. Klepetko; E. Kubista; G. Boltz-Nitulescu; K. Lechner; P. Valent
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 688 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0939-5555
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The growth and differentiation in vitro of rodent mast cells, a process dependent upon interleukin (IL)-3, has already been well established. Only recently, however, have the mechanisms underlying the development in vitro of human metachromatic cells (basophils and mast cells) begun to be delineated
Previously we have reported that rodent mast cells synthesize the mRNA encoding the u and f 3 integrin chains (u4, 61 and (37) of the lymphocyte Peyer's patch adhesion molecule (LPAM)-1 and LPAM-2 lymphocyte homing receptors, and that they possess an a4-containing integrin complex on their cell surf