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Differential expression of a recombinant adeno-associated virus 2 vector in human CD34+ cells and breast cancer cells

✍ Scribed by Veldwijk, Marlon R; Fruehauf, Stefan; Schiedlmeier, Bernhard; Kleinschmidt, Juergen A; Zeller, W Jens


Book ID
110017697
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
191 KB
Volume
7
Category
Article
ISSN
0929-1903

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## Abstract ## Background Adeno‐associated virus (AAV) vectors have been shown to correct a variety of mutations in human cells by homologous recombination (HR) at high rates, which can overcome insertional mutagenesis and transgene silencing, two of the major hurdles in conventional gene addition